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Stroke Awareness

Visit the Know Stroke website to learn more about stroke and obtain Know Stroke materials such as brochures, posters, and this video.

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Healthy Brain Aging

The NINDS investigator community is passionate about discovering new and better ways of preventing and treating stroke as well as improving recovery in those who suffer stroke. High blood pressure, the primary driver of stroke, is thought to impart physiological damage on blood vessels in the brain. This damage can lead to ischemic and hemorrhagic stroke and even “silent strokes”—small infarcts that go relatively unnoticed, but which affect nearly 30 percent of elderly individuals. In addition to the well-known burden of illness due to clinical stroke, decades of research has also shown a causative link between stroke and cognitive impairment and dementia later in life.

Hypertension can also lead to “diffuse white matter disease” where the various bundles of fibers that connect brain regions are compromised by disease in the small blood vessels that supply the center of the brain. These abnormalities, which appear on MRI brain scans as coalescing, multiple bright spots in deep structures of the brain, affect as many as 80 percent of those over age 80, but their number, size, severity and rate of progression vary. Higher blood pressure levels over time have been linked to more extensive areas of white matter damage, which itself has been linked to diminished performance on tests of cognitive function. Read More ...


Labs at NINDS

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  • NIH Blueprint Requests for Information
  • Activating stem cells may repair brain injury in Multiple Sclerosis
  • BRAIN Working Group Publishes Article in Royal Society
  • A Spotlight on Rigorous Study Design and Transparent Reporting
  • BRAIN Initiative Funding Opportunities
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